More drugs...things surely have changed eh. Got an email today that speaks to a new drug that could get FDA approval by December 2010. wow and this one is oral! Will i switch? nah...If Tysabri will still be the most aggressive on the market, I'll give it a chance. Now had I still been taking my "daily" shot, then HELL YEAH - no questions asked, i would have switched. Tysabri is monthly; I can handle it - even tho my veins like to play Hde & Seek!